Medical Research
MEDICAL RESEARCH
For more than forty years, Texas Back Institute is committed to providing the highest quality treatments and services for our patients. Our clinical research team stays at the forefront of medical care by initiating studies that advance patient outcomes over time.
Patients can access the latest in clinical studies, peer-reviewed papers, and advanced technology that address trauma, deformity, tumors, and age-related degenerative changes. In some cases, patients are granted access to clinical trials in motion-preserving, minimally invasive and robotics to support their course of treatment
The Spine Biomechanics Laboratory at Texas Back Institute exists to investigate the biomechanical and neuromuscular risk factors associated with spinal ailments in an effort to define the most appropriate and effective treatment options.
This lab is a critical component in bridging the basic science of biomechanics and engineering with the clinical science of spinal care. The clinicians and scientists involved with the lab are uncompromising in furthering the treatment of spinal pathology and translating that knowledge into advanced care to for the patients we serve.
Clinical Research Articles
Cervical
Lumbar
Spine Biomechanics Lab
- “Long-term clinical and radiographic outcomes of cervical disc replacement with the Prestige disc: results from a prospective randomized controlled clinical trial” posted in the Journal Neurosurgery Spine (Dr. Zigler)
http://thejns.org/doi/full/10.3171/2010.3.SPINE09513 - “Cervical total disc replacement with the Mobi-C cervical artificial disc compared with anterior discectomy and fusion for treatment of 2-level symptomatic degenerative disc disease: a prospective, randomized, controlled multicenter clinical trial” posted in the Journal Neurosurgery Spine (Drs. Hisey and Rashbaum)
http://thejns.org/doi/full/10.3171/2013.6.SPINE12527 - “Prospective, Randomized Comparison of Cervical Total Disc Replacement vs. Anterior Cervical Fusion: Results at 48 Months Follow-up” posted in Journal of Spinal Disorders and Techniques (Dr. Hisey)
http://journals.lww.com/jspinaldisorders/Fulltext/2015/05000/Prospective,_Randomized_Comparison_of_Cervical.16.aspx - “Comparison of 2 Lumbar Total Disc Replacements: Results of a Prospective, Randomized, Controlled, Multicenter Food and Drug Administration Trial With 24-Month Follow-up” posted in the Spine Journal (Dr. Guyer)
http://journals.lww.com/spinejournal/Abstract/2014/05200/Comparison_of_2_Lumbar_Total_Disc_Replacements_.2.aspx - “Results of the prospective, randomized, controlled multicenter Food and Drug Administration investigational device exemption study of the ProDisc-C total disc replacement versus anterior discectomy and fusion for the treatment of 1-level symptomatic cervical disc disease” posted in The Spine Journal (Dr. Zigler)
http://www.thespinejournalonline.com/article/S1529-9430(08)00201-5/abstract
- “Five-year follow-up of total disc replacement compared to fusion: a randomized controlled trial” posted in the European Spine Journal (Drs. Blumenthal, Zigler, and Guyer)
http://link.springer.com/article/10.1007/s00586-013-2926-y - “Five-year results of the prospective, randomized, multicenter, Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement versus circumferential arthrodesis for the treatment of single-level degenerative disc disease” posted in the Journal Neurosurgery Spine (Dr. Zigler)
http://thejns.org/doi/full/10.3171/2012.9.SPINE11498 - “Five-year adjacent-level degenerative changes in patients with single-level disease treated using lumbar total disc replacement with ProDisc-L versus circumferential fusion” posted in the Journal Neurosurgery Spine (Dr. Zigler)
http://thejns.org/doi/full/10.3171/2012.9.SPINE11717 - “Prospective, Randomized, Multicenter Food and Drug Administration Investigational Device Exemption Study of the ProDisc-L Total Disc Replacement Compared with Circumferential Arthrodesis for the Treatment of Two-Level Lumbar Degenerative Disc Disease” posted in the Journal of Bone and Joint Surgery (Dr. Zigler)
- “A Prospective, Randomized, Multicenter Food and Drug Administration Investigational Device Exemptions Study of Lumbar Total Disc Replacement With the CHARITÉ™ Artificial Disc Versus Lumbar Fusion” posted in the Spine journal (Dr. Blumenthal)
http://journals.lww.com/spinejournal/Abstract/2005/07150/A_Prospective,_Randomized,_Multicenter_Food_and.3.aspx - “Prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of lumbar total disc replacement with the CHARITE´ artificial disc versus lumbar fusion: Five-year follow-up” posted in The Spine Journal (Dr. Guyer)
http://www.thespinejournalonline.com/article/S1529-9430(08)00849-8/abstract - “A Prospective, Randomized, Multicenter Food and Drug Administration Investigational Device Exemption Study of Lumbar Total Disc Replacement With the CHARITÉ™ Artificial Disc Versus Lumbar Fusion” posted in the Spine Journal (Drs. Guyer and Blumenthal)
http://journals.lww.com/spinejournal/Abstract/2005/07150/A_Prospective,_Randomized,_Multicenter_Food_and.4.aspx
“Results of the Prospective, Randomized, Multicenter Food and Drug Administration Investigational Device Exemption Study of the ProDisc -L Total Disc Replacement Versus Circumferential Fusion for the Treatment of 1-Level Degenerative Disc Disease” posted in the Spine Journal (Dr. Zigler)
http://journals.lww.com/spinejournal/Abstract/2007/05150/Results_of_the_Prospective,_Randomized,.2.aspx
- Haddas R, Cox J, Belanger T, Boah AO, Ju KL, Derman PB. (2019) Characterizing Gait Abnormalities in Patients with Cervical Spondylotic Myelopathy: A Neuromuscular Analysis. The Spine Journal; 16(11): 1803-08. DOI: 10.1016/j.spinee.2019.06.005
- Haddas R, Lieberman IH. (2019) The Change in Sway and Neuromuscular Activity in Adult Degenerative Scoliosis Patients Pre and Post Surgery Compared to Controls. Spine; 44(15): E899-907. DOI: 10.1097/BRS.0000000000003009
- Haddas R, Xu M, Lieberman IH, Yang J. (2019) Finite Element Analysis of Pre and Post Lumbar Fusion for Adult Degenerative Scoliosis Patients. Spine Deformity; 7(4): 543-52. DOI: 10.1016/j.jspd.2018.11.008
- Xu M, Yang J, Lieberman IH, Haddas R. (2019) Finite Element Method-Based Study of Pedicle Screw-Bone Interaction. Medical Engineering & Physics; 67: 11-21. DOI: 10.1016/j.medengphy.2019.03.004
- Haddas R, Lieberman IH, Kakar R. (2019) A Comparison of Muscular Activity during Gait between Walking Sticks and a Walker in Patients with Adult Degenerative Scoliosis. Spinal Deformity; 7:454-466. DOI: 10.1016/j.jspd.2018.09.067
- Xu M, Yang J, Lieberman IH, Haddas R. (2019) The Effect of Surgical Alignment in Adult Scoliotic Spines on Axial Cyclic Vibration: A Finite Element Study. Journal of Computing and Information Science in Engineering; 19(2): 021006. DOI: 10.1115/1.4042326
- Haddas R, Lieberman IH, Arakal R, Boah A, Belanger T, Ju KL. (2019) Effect of Cervical Decompression Surgery on Gait in Adult Cervical Spondylotic Myelopathy Patients. Clinical Spine Surgery; 31(10): 435-40. DOI: 10.1097/BSD.0000000000000719
- Xu M, Yang J, Lieberman, IH, Haddas R. (2019) Comparisons of Stress Distributions in Vertebral Bone and Pedicle Screw and Screw-Bone Load Transfers among Different Fixation Methods of Lumbar Spine Fusion Surgery: A Finite Element Study. Medical Engineering and Physics, 63, 2019, 26-32. DOI: 10.1016/j.medengphy.2018.10.003
- Haddas R, Lieberman IH, Boah A, Arakal R, Belanger T, Ju KL. (2019) Functional Balance Testing in Cervical Spondylotic Myelopathy Patients. Spine; 44(2): 103-109. DOI: 10.1097/BRS.0000000000002768
- Haddas R, Ju KL. (2018) Gait Alteration in Cervical Spondylotic Myelopathy Elucidated By Ground Reaction Forces. Spine; 44(1): 25-31. DOI: 10.1097/BRS.0000000000002732
- Xu M, James Y, Lieberman IH, Haddas R. (2019) Stress Distribution in Vertebral Bone and Pedicle Screw and Screw-Bone Load Transfers among Various Fixation Methods for Lumbar Spine Surgical Alignment: A Finite Element Study. Medical Engineering & Physics; 63: 26-32. DOI: 10.1016/j.medengphy.2018.10.003
- Haddas R, Lieberman IH, Block A. (2018) The Relationship between Fear-Avoidance and Neuromuscular Measures of Function in Patients with Adult Degenerative Scoliosis. Spine; 43(23): E1412-21. DOI: 10.1097/BRS.0000000000002719
- Haddas R, Patel S, Arakal R, Boah AO, Belanger T, Ju KL. (2018) Spine and Lower Extremity Kinematics during Gait in Cervical Spondylotic Myelopathy Patients. The Spine Journal; 18(9): 1645-1652. DOI: 10.1016/j.spinee.2018.04.006
- Haddas R, Ju K, Lieberman IH. (2018) The Use of Gait Analysis in the Evaluation of Patients Afflicted with Spinal Disorders. European Spine Journal; 27(8): 1712-1723. DOI: 10.1007/s00586-018-5569-1
- Haddas R, Lieberman IH. (2018) A Method to Quantify the “Cone of Economy”. European Spine Journal; 27(5): 1178-1187. DOI: 10.1007/s00586-018-5475-6
- Haddas R, Lieberman IH, Block A. (2018) The Relationship between Fear-Avoidance and Objective Biomechanical Measures of Function in Patients with Adult Degenerative Scoliosis. Spine, 46 (9): 647-653. DOI: 10.1097/BRS.0000000000002381
- Aghyarian S, Hu X, Haddas R, Lieberman IH, Kosmopoulos V, Kim HKW, Rodrigues DC. (2017) Biomechanical behavior of novel composite PMMA-CaP bone cements in an anatomically accurate cadaveric vertebroplasty model. Journal of Orthopaedic Research; 35(9); 2067-2074. DOI: 10.1002/jor.23491
- Haddas R, Belanger T. (2017) Clinical Gait Analysis on a Patient Undergoing Surgical Correction of Kyphosis from Severe Ankylosing Spondylitis. International Journal of Spine Surgery; 11(3): 138-144. DOI: 10.14444/4018
- Haddas R, Hu X, Lieberman IH. The Correlation of Spinopelvic Parameters with Biomechanical Parameters Measured by Gait and Balance Analyses in Patients with Adult Degenerative Scoliosis. Clinical Spine Surgery; In Press.
- Haddas R, Ju KL, Boah AO, Kosztowski T, Derman PB. The Effect of Surgical Decompression on Functional Balance Testing in Patients with Cervical Spondylotic Myelopathy. Clinical Spine Surgery; In Press. DOI: 10.1097/BSD.0000000000000889
- Haddas R, Samocha Y, Yang J. Effects of Volitional Spine Stabilization on Trunk Control during Asymmetric Lifting Task in Patients with Recurrent Low Back Pain. Global Spine Journal; In Press. DOI: 10.1177/2192568219885898