Texas Back Institute Clinical Research, LLC
Texas Back Institute Clinical Research, LLC is an organization dedicated to advancing new spinal technologies and techniques at Texas Back Institute. The organization’s experienced clinical research coordinators supervise clinical research trials, research studies and education programs with the physicians of Texas Back Institute. Texas Back Institute Clinical Research was formed in 2004, and has been involved in more than 20 clinical trials
The Texas Back Institute Research Foundation (TBIRF) was founded in 1985 to fulfill the mission of improving care for patients with back pain through research and education. With the collaborative efforts of multiple spine centers nationally and internationally, TBIRF has performed research focused primarily on diagnostic evaluations and treatment outcomes. This work has included topics such as discography, pre-surgical psychosocial screening and new technologies such as total disc replacements and minimally invasive surgical procedures. The findings from the research work are shared with peers through presentations at numerous national and international spine conferences, and have been published in respected medical journals such as Spine, The Spine Journal, the Journal of Neurosurgery, and the Journal of Bone and Joint Surgery.
The Foundation has organized the publication of multiple textbooks including Sports and the Spine and Spinal Arthroplasty: A New Era in Spine Care, which was the first book published on the topic of motion-preserving technologies in spine.
Not only does TBIRF provide information to peers through journal publications, books and conference presentations, it also provides education to individual physicians through fellowships and visitor programs. To date, more than 100spine surgeons have trained through the TBIRF Fellowship Program and now practice throughout the United States. The program includes participation in spine clinics, surgical cases, research, Continuing Medical Education accredited journal clubs, informative case conferences and hands-on surgical training courses. Additionally, TBIRF has hosted visiting spine surgeons and research fellows from Europe, Asia and South America.
TBIRF is dedicated to improving care for those with back pain by continuously performing research, participating in conferences, publishing and offering a wide array of individual educational programs.
Clinical Trials
Our goal at Texas Back Institute Clinical Research is to improve the overall quality of life for patients suffering with spine-related health issues. To assist us in achieving this goal, we participate in FDA clinical trials for investigational technologies, materials, drugs and devices.
Basic Science
The Spine Biomechanics Laboratory at Texas Back Institute exists to investigate the biomechanical and neuromuscular risk factors associated with spinal ailments in an effort to define the most appropriate and effective treatment options.
This lab is a critical component in bridging the basic science of biomechanics and engineering, with the clinical science of treating patients suffering from spinal ailments.
The clinicians and scientists involved with the lab are uncompromising in furthering the biomechanics related to the treatment of spinal pathology. They will make every effort to further the science and translate that knowledge into clinical advances which will benefit the patients we serve.
Clinical Research Articles
Cervical
- “Long-term clinical and radiographic outcomes of cervical disc replacement with the Prestige disc: results from a prospective randomized controlled clinical trial” posted in the Journal Neurosurgery Spine (Dr. Zigler)
http://thejns.org/doi/full/10.3171/2010.3.SPINE09513 - “Cervical total disc replacement with the Mobi-C cervical artificial disc compared with anterior discectomy and fusion for treatment of 2-level symptomatic degenerative disc disease: a prospective, randomized, controlled multicenter clinical trial” posted in the Journal Neurosurgery Spine (Drs. Hisey and Rashbaum)
http://thejns.org/doi/full/10.3171/2013.6.SPINE12527 - “Prospective, Randomized Comparison of Cervical Total Disc Replacement vs. Anterior Cervical Fusion: Results at 48 Months Follow-up” posted in Journal of Spinal Disorders and Techniques (Dr. Hisey)
http://journals.lww.com/jspinaldisorders/Fulltext/2015/05000/Prospective,_Randomized_Comparison_of_Cervical.16.aspx - “Comparison of 2 Lumbar Total Disc Replacements: Results of a Prospective, Randomized, Controlled, Multicenter Food and Drug Administration Trial With 24-Month Follow-up” posted in the Spine Journal (Dr. Guyer)
http://journals.lww.com/spinejournal/Abstract/2014/05200/Comparison_of_2_Lumbar_Total_Disc_Replacements_.2.aspx - “Results of the prospective, randomized, controlled multicenter Food and Drug Administration investigational device exemption study of the ProDisc-C total disc replacement versus anterior discectomy and fusion for the treatment of 1-level symptomatic cervical disc disease” posted in The Spine Journal (Dr. Zigler)
http://www.thespinejournalonline.com/article/S1529-9430(08)00201-5/abstract
Lumbar
- “Five-year follow-up of total disc replacement compared to fusion: a randomized controlled trial” posted in the European Spine Journal (Drs. Blumenthal, Zigler, and Guyer)
http://link.springer.com/article/10.1007/s00586-013-2926-y - “Five-year results of the prospective, randomized, multicenter, Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement versus circumferential arthrodesis for the treatment of single-level degenerative disc disease” posted in the Journal Neurosurgery Spine (Dr. Zigler)
http://thejns.org/doi/full/10.3171/2012.9.SPINE11498 - “Five-year adjacent-level degenerative changes in patients with single-level disease treated using lumbar total disc replacement with ProDisc-L versus circumferential fusion” posted in the Journal Neurosurgery Spine (Dr. Zigler)
http://thejns.org/doi/full/10.3171/2012.9.SPINE11717 - “Prospective, Randomized, Multicenter Food and Drug Administration Investigational Device Exemption Study of the ProDisc-L Total Disc Replacement Compared with Circumferential Arthrodesis for the Treatment of Two-Level Lumbar Degenerative Disc Disease” posted in the Journal of Bone and Joint Surgery (Dr. Zigler)
http://jbjs.org/content/93/8/705 - “A Prospective, Randomized, Multicenter Food and Drug Administration Investigational Device Exemptions Study of Lumbar Total Disc Replacement With the CHARITÉ™ Artificial Disc Versus Lumbar Fusion” posted in the Spine journal (Dr. Blumenthal)
http://journals.lww.com/spinejournal/Abstract/2005/07150/A_Prospective,_Randomized,_Multicenter_Food_and.3.aspx - “Prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of lumbar total disc replacement with the CHARITE´ artificial disc versus lumbar fusion: Five-year follow-up” posted in The Spine Journal (Dr. Guyer)
http://www.thespinejournalonline.com/article/S1529-9430(08)00849-8/abstract - “A Prospective, Randomized, Multicenter Food and Drug Administration Investigational Device Exemption Study of Lumbar Total Disc Replacement With the CHARITÉ™ Artificial Disc Versus Lumbar Fusion” posted in the Spine Journal (Drs. Guyer and Blumenthal)
http://journals.lww.com/spinejournal/Abstract/2005/07150/A_Prospective,_Randomized,_Multicenter_Food_and.4.aspx - “Results of the Prospective, Randomized, Multicenter Food and Drug Administration Investigational Device Exemption Study of the ProDisc -L Total Disc Replacement Versus Circumferential Fusion for the Treatment of 1-Level Degenerative Disc Disease” posted in the Spine Journal (Dr. Zigler)
http://journals.lww.com/spinejournal/Abstract/2007/05150/Results_of_the_Prospective,_Randomized,.2.aspx
ABOUT TEXAS BACK INSTITUTE
Texas Back Institute uses its experience, talent, state-of-the-art equipment, and technology to provide superior and innovative care for patients who suffer from back and neck pain.
